Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.68 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.60 |
| ▸ | TUBB | P07437 | 3/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865449 | 0.95 | NPC1 (0.65) | SPHK2SPHK1NPC1RAB9AALDH1A1 | |
| SCHEMBL11868109 | 0.90 | TUBB4A (0.65) | SPHK2SPHK1NPC1RAB9AALDH1A1 | |
| SCHEMBL11811484 | 0.86 | RAB9A (0.51) | SPHK2SPHK1NPC1RAB9AALDH1A1 | |
| Lobendazole SCHEMBL29682294 | 0.84 | LMNA (0.64) | SPHK2SPHK1NPC1RAB9AALDH1A1 | |
| Lobendazole SCHEMBL205437 | 0.84 | LMNA (0.64) | SPHK2SPHK1NPC1RAB9AALDH1A1 | |
| SCHEMBL11715582 | 0.84 | SPHK2 (0.60) | SPHK2SPHK1NPC1RAB9AALDH1A1 | |
| SCHEMBL11805605 | 0.84 | CYP3A4 (0.60) | SPHK2SPHK1NPC1RAB9AALDH1A1 | |
| Carbendazim SCHEMBL11739819 | 0.83 | SPHK2 (0.59) | SPHK2SPHK1NPC1RAB9AALDH1A1 | |
| SCHEMBL22401 | 0.83 | LMNA (0.56) | SPHK2SPHK1NPC1RAB9AALDH1A1 | |
| SCHEMBL30084551 | 0.83 | LMNA (0.56) | SPHK2SPHK1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933846-A | FUNGICIDES, OVICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |