SCHEMBL1180183

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1180851	0.95	HSD17B1 (0.54)	HSD17B1HSD17B2CYP3A4CYP2C9MMP2
	SCHEMBL1181058	0.92	HSD17B1 (0.59)	HSD17B1HSD17B2CYP3A4CYP2C9DYRK1A
	SCHEMBL28743481	0.89	KDM4E (0.56)	HSD17B1HSD17B2CYP3A4CYP2C9MMP2
	SCHEMBL1180159	0.89	APP (0.57)	HSD17B1HSD17B2CYP3A4CYP2C9MMP2
	SCHEMBL2225106	0.87	HSD17B1 (0.48)	HSD17B1HSD17B2CYP3A4CYP2C9MMP2
	SCHEMBL6693612	0.82	ACHE (0.57)	HSD17B1HSD17B2CYP3A4CYP2C9DYRK1A
	SCHEMBL16493394	0.82	MMP2 (0.51)	CYP3A4CYP2C9MMP2MMP9DYRK1A
	SCHEMBL2603423	0.82	MMP2 (0.51)	CYP3A4CYP2C9MMP2MMP9DYRK1A
	SCHEMBL4257417	0.80	CSNK2A2 (0.57)	HSD17B1HSD17B2CYP3A4CYP2C9MMP2
	SCHEMBL1180781	0.79	APP (0.74)	HSD17B1HSD17B2CYP3A4CYP2C9DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.