Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30187201 | 1.00 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL8064140 | 0.82 | ALDH1A1 (0.44) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9230966 | 0.79 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL20119833 | 0.77 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6886 | 0.77 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL15478544 | 0.77 | RAPGEF4 (0.50) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27614646 | 0.76 | CA3 (0.42) | MAPTALDH1A1MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL837448 | 0.76 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL20620435 | 0.74 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL8943130 | 0.74 | MEN1 (0.42) | MAPTALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954852-A | Indenylacetic acid compounds | MERCK & CO., INC. (US) | 1976-05-04 | — | — | US | disclosed |