Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766960 | 0.87 | PKM (0.47) | PKMPLA2G4BMAPK1TSHRTP53 | |
| SCHEMBL11870994 | 0.86 | GAA (0.54) | MAPK1RAB9ASMN1; SMN2SRD5A2HTT | |
| SCHEMBL7767571 | 0.83 | SRD5A2 (0.51) | PKMPLA2G4BMAPK1TSHRTP53 | |
| SCHEMBL7766997 | 0.83 | SRD5A2 (0.51) | PKMPLA2G4BMAPK1TSHRTP53 | |
| SCHEMBL7763847 | 0.81 | RXRA (0.47) | PKMPLA2G4BMAPK1TSHRTP53 | |
| SCHEMBL7771473 | 0.80 | SRD5A2 (0.48) | PKMPLA2G4BMAPK1TSHRTP53 | |
| SCHEMBL11571027 | 0.80 | CA12 (0.47) | TSHRNPC1CA1CA2 | |
| SCHEMBL1964361 | 0.78 | CA2 (0.43) | PKMPLA2G4BMAPK1TSHRTP53 | |
| SCHEMBL1966013 | 0.78 | CA2 (0.43) | PKMPLA2G4BMAPK1TSHRTP53 | |
| SCHEMBL21197731 | 0.78 | CA2 (0.43) | PKMPLA2G4BMAPK1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051319-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-3957833-A | KILLING INSECTS, HORMONES | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | disclosed |