Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130672 | 0.93 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HSD17B10HPGDNR3C2 | |
| SCHEMBL15505827 | 0.86 | ALDH1A1 (0.66) | ALDH1A1CYP3A4HSD17B10HPGDSNCA | |
| SCHEMBL29706072 | 0.86 | ALDH1A1 (0.66) | ALDH1A1CYP3A4HSD17B10HPGDSNCA | |
| SCHEMBL158574 | 0.85 | NR3C2 (0.60) | ALDH1A1CYP3A4HSD17B10HPGDNR3C2 | |
| SCHEMBL15089232 | 0.85 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HSD17B10HPGDNR3C2 | |
| SCHEMBL1576428 | 0.83 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HSD17B10HPGDNR3C2 | |
| SCHEMBL10687496 | 0.81 | ESR1 (0.54) | ALDH1A1CYP3A4NR3C2ESR1ESR2 | |
| SCHEMBL11466814 | 0.81 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10HPGDSNCA | |
| SCHEMBL8626323 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HSD17B10HPGDNR3C2 | |
| SCHEMBL29354421 | 0.81 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10HPGDSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3944492-A | Lubricant compositions containing N-substituted naphthylamines as antioxidants | UNIROYAL, INC. (US) | 1976-03-16 | — | — | US | claimed |
| US-3944492-A | Lubricant compositions containing N-substituted naphthylamines as antioxidants | UNIROYAL, INC. (US) | 1976-03-16 | — | — | US | disclosed |