SCHEMBL1576428

SCHEMBL1576428

CC(C)(c1ccccc1)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.59
HSD17B10 Q99714 5/20 0.59
ALOX12 P18054 4/20 0.59
L3MBTL1 Q9Y468 4/20 0.59
TSHR P16473 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
ALOX15 P16050 2/20 0.59
PTGS1 P23219 1/20 0.59
SLC6A2 P23975 1/20 0.59
MAPK1 P28482 1/20 0.59
PTGS2 P35354 1/20 0.59
HTR2B P41595 1/20 0.59
NR3C2 P08235 3/20 0.58
CYP3A4 P08684 6/20 0.56
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
HPGD P15428 4/20 0.54
LMNA P02545 1/20 0.48
THRB P10828 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158574 0.98 NR3C2 (0.60) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL8626323 0.98 ALDH1A1 (0.62) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL471147 0.91 NR3C2 (0.55) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL26411228 0.90 NR3C2 (0.53) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL26411224 0.90 NR3C2 (0.53) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL14571901 0.90 HPGD (0.65) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL22432455 0.87 NR3C2 (0.50) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL10776423 0.87 HPGD (0.68) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL14136110 0.85 NR3C2 (0.49) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL12278122 0.85 NR3C2 (0.54) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686172-B1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEM CO INC (US) 2000-11-08 EP claimed
EP-0686172-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1995-12-13 EP claimed
WO-1994019404-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-01 WO claimed
US-5308884-A Mixture of dimethylbenzyl substituted diphenylamines, improved scorch resistance, hydrolytic and color stability UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-05-03 US claimed
US-5269961-A Dimethylbenzyl diphenylamine stabilizers UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-12-14 US claimed
JP-54068898-A None JP disclosed
WO-2025132945-A1 LUBRICANT COMPOSITIONS CONTAINING ARALKYL SUBSTITUTED DIPHENYLAMINE ANTIOXIDANT INFINEUM INTERNATIONAL LIMITED (GB) 2025-06-26 WO disclosed
CN-116438290-A Structured premixes and liquid compositions containing them 宝洁公司 2023-07-14 CN disclosed
US-20230130802-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-04-27 US disclosed
US-20230130802-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-04-27 US disclosed
US-20180171105-A1 RUBBER COMPOSITION THAT CAN BE CROSS-LINKED BY MEANS OF AMINE AND THAT HAS A LIGHT-COLORED FILLER Schill+Seilacher "Struktol" GmbH (DE) 2018-06-21 US disclosed
US-8785534-B2 Use of polyamides that are resistant to corrosion and stress cracking BASF SE (DE) 2014-07-22 US disclosed
US-5308884-A Mixture of dimethylbenzyl substituted diphenylamines, improved scorch resistance, hydrolytic and color stability UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-05-03 US disclosed
US-5269961-A Dimethylbenzyl diphenylamine stabilizers UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-12-14 US disclosed
US-5269961-A Dimethylbenzyl diphenylamine stabilizers UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-12-14 US disclosed
EP-0317814-B1 OIL RESISTANT THERMOPLASTIC ELASTOMER POLYSAR LIMITED (CA) 1992-05-20 EP disclosed
US-4956398-A CRACK RESISTANCE FOR MECHANICAL GOODS POLYSAR LIMITED (CA) 1990-09-11 US disclosed
EP-0317814-A1 Oil resistant thermoplastic elastomer POLYSAR LIMITED (CA) 1989-05-31 EP disclosed
US-4438230-A VULCANIZABLE POLYSAR LIMITED (CA) 1984-03-20 US disclosed
JP-S5468898-A LOW-DENSITY NON-RIGID URETHANE FOAM AND ITS MANUFACTURE BRIDGESTONE CORP 1979-06-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230130802-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, ELAVL1, EML4 ALDH1A1 861/4885HSD17B10 4537/4885ALOX12 1016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.