SCHEMBL8626323

SCHEMBL8626323

CC(C)(c1ccc(Nc2ccccc2)cc1)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.62
HSD17B10 Q99714 5/20 0.62
ALOX12 P18054 4/20 0.62
L3MBTL1 Q9Y468 4/20 0.62
TSHR P16473 3/20 0.62
TDP1 Q9NUW8 3/20 0.62
ALOX15 P16050 2/20 0.62
PTGS1 P23219 1/20 0.62
SLC6A2 P23975 1/20 0.62
MAPK1 P28482 1/20 0.62
PTGS2 P35354 1/20 0.62
HTR2B P41595 1/20 0.62
HPGD P15428 4/20 0.56
NR3C2 P08235 3/20 0.55
CYP3A4 P08684 6/20 0.52
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
MAPT P10636 6/20 0.50
CYP1A2 P05177 3/20 0.50
CYP2C9 P11712 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576428 0.98 ALDH1A1 (0.59) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL158574 0.95 NR3C2 (0.60) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL471147 0.89 NR3C2 (0.55) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL22432455 0.89 NR3C2 (0.50) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL26411228 0.87 NR3C2 (0.53) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL14571901 0.87 HPGD (0.65) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL26411224 0.87 NR3C2 (0.53) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
Diphenylamine SCHEMBL29287150 0.86 ALDH1A1 (0.62) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL502030 0.86 ALDH1A1 (0.62) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL10776423 0.85 HPGD (0.68) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4714779-A Aromatic aryl amine polymers XEROX CORPORATION (US) 1987-12-22 US claimed
EP-0052961-B1 AMINE POLYMERS AND IMAGING MEMBERS CONTAINING AMINE POLYMERS XEROX CORPORATION (US) 1985-09-11 EP claimed
EP-0052961-A1 Amine polymers and imaging members containing amine polymers XEROX CORPORATION (US) 1982-06-02 EP claimed
CN-108226345-B A kind of method of BNST pollutant in detection environment 哈尔滨工业大学 2018-11-30 CN disclosed
CN-108051526-B A kind of method of PREPOD pollutants in detection environment 哈尔滨工业大学 2018-10-30 CN disclosed
CN-107957472-B A kind of method of BENPAT pollutants in detection environment 哈尔滨工业大学 2018-10-30 CN disclosed
CN-108226345-A A kind of method of BNST pollutants in detection environment 哈尔滨工业大学 2018-06-29 CN disclosed
CN-108051526-A A kind of method of PREPOD pollutants in detection environment 哈尔滨工业大学 2018-05-18 CN disclosed
CN-107957472-A A kind of method of BENPAT pollutants in detection environment 哈尔滨工业大学 2018-04-24 CN disclosed
US-20100028047-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS SHARP KABUSHIKI KAISHA (JP) 2010-02-04 US disclosed
EP-0452681-B1 Electrostatographic imaging member containing polyarylamine polymers XEROX CORP (US) 1998-06-03 EP disclosed
US-4801517-A Polyarylamine compounds and systems utilizing polyarylamine compounds XEROX CORPORATION (US) 1989-01-31 US disclosed
EP-0295113-A2 Polyarylamine compounds XEROX CORPORATION (US) 1988-12-14 EP disclosed
US-4764625-A POTASSIUM HYDROXIDE, COPPER CATALYST XEROX CORPORATION (US) 1988-08-16 US disclosed
US-4714779-A Aromatic aryl amine polymers XEROX CORPORATION (US) 1987-12-22 US disclosed
EP-0052961-B1 AMINE POLYMERS AND IMAGING MEMBERS CONTAINING AMINE POLYMERS XEROX CORPORATION (US) 1985-09-11 EP disclosed
EP-0034425-B1 PROCESS FOR PREPARING ARYLAMINES XEROX CORPORATION (US) 1984-05-16 EP disclosed
EP-0099516-A1 Process for the preparation of bis(aminocyclohexyl)dialkyl methanes BASF Aktiengesellschaft (DE) 1984-02-01 EP disclosed
EP-0052961-A1 Amine polymers and imaging members containing amine polymers XEROX CORPORATION (US) 1982-06-02 EP disclosed
EP-0034425-A2 Process for preparing arylamines XEROX CORPORATION (US) 1981-08-26 EP disclosed