Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Altretamine SCHEMBL13723253 | 0.80 | ALDH1A1 (0.55) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| Altretamine SCHEMBL20539080 | 0.77 | LMNA (0.61) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL515345 | 0.77 | CYP1A2 (0.42) | POLBALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL10468490 | 0.76 | POLB (0.43) | POLBALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL2474178 | 0.73 | POLB (0.60) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL3759813 | 0.73 | POLB (0.60) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL17451136 | 0.72 | POLB (0.58) | POLBALDH1A1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL11802135 | 0.71 | KMT2A (0.38) | POLBKDM4ELMNACYP1A2TSHR | |
| SCHEMBL11801853 | 0.71 | KMT2A (0.38) | POLBALDH1A1KDM4ECYP1A2GAA | |
| SCHEMBL2475847 | 0.71 | POLB (0.51) | POLBALDH1A1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940365-A | PHENOLIC ANTIOXIDANT AND AN UREA OR AN OXALIC ACID DIAMIDE OR AN AZODICARBOXYLIC AMIDE | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | disclosed |