SCHEMBL515345

SCHEMBL515345

NC(=O)Nc1nc(NC(N)=O)nc(NC(N)=O)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
APP P05067 2/20 0.40
ACHE P22303 2/20 0.40
PEPD P12955 1/20 0.39
KMT2A Q03164 3/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 3/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 3/20 0.37
TSHR P16473 2/20 0.37
NFKB1 P19838 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
THPO P40225 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11592921 0.89 CYP1A2 (0.38) CYP1A2APPACHEPEPDKMT2A
SCHEMBL11801853 0.87 KMT2A (0.38) CYP1A2APPACHEPEPDKMT2A
SCHEMBL3470061 0.84 CYP1A2 (0.42) CYP1A2APPACHEPEPDKMT2A
SCHEMBL3025720 0.84 CYP1A2 (0.38) CYP1A2APPACHEPEPDKMT2A
SCHEMBL7611193 0.82 LMNA (0.41) CYP1A2APPACHEKMT2AGAA
SCHEMBL11802135 0.82 KMT2A (0.38) CYP1A2APPACHEPEPDKMT2A
SCHEMBL12421833 0.82 L3MBTL1 (0.58) CYP1A2KMT2AGAAKDM4EHTT
SCHEMBL9505940 0.80 PEPD (0.40) CYP1A2APPACHEPEPDKMT2A
SCHEMBL19166215 0.78 APP (0.34) CYP1A2APPACHEKMT2AMAPK1
SCHEMBL10616487 0.78 MAPT (0.58) CYP1A2KMT2AKDM4EHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070189991-A1 Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment L'OREAL S.A. (FR) 2007-08-16 US claimed
EP-1797868-A1 Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment L'Oréal (FR) 2007-06-20 EP claimed
EP-1797867-A1 Cosmetic or pharmaceutical composition comprising a copolymer containing at least one ionisable group, and cosmetic treatment L'Oréal (FR) 2007-06-20 EP claimed
CN-110023380-B Aqueous dispersions of polyolefin supramolecular polymers and their use in cosmetics 莱雅公司 2022-10-04 CN disclosed
CN-110494122-B Process for dyeing hair comprising pigment and supramolecular polymer aqueous dispersion 莱雅公司 2022-09-27 CN disclosed
EP-3548544-B1 AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS OREAL (FR) 2021-07-21 EP disclosed
US-10973751-B2 Hair dyeing process comprising a pigment and an aqueous dispersion of supramolecular polymer L'OREAL (FR) 2021-04-13 US disclosed
US-20200108007-A1 HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER L'OREAL (FR) 2020-04-09 US disclosed
EP-3606502-A1 HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER L'Oreal (FR) 2020-02-12 EP disclosed
EP-3548544-A1 AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS L'OREAL (FR) 2019-10-09 EP disclosed
US-20190274946-A1 AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS L'OREAL (FR) 2019-09-12 US disclosed
US-20100154134-A1 COMPOSITION FOR DYEING KERATIN FIBERS, COMPRISING AT LEAST ONE POLYALKENE-BASED SUPRAMOLECULAR POLYMER, AT LEAST ONE PIGMENT AND AT LEAST ONE VOLATILE SOLVENT L'OREAL S.A. (FR) 2010-06-24 US disclosed
WO-2010057920-A2 METHOD FOR MAKING UP OR CARING FOR EYELASHES OR EYEBROWS USING A POLYALKENE-BASED SUPRAMOLECULAR POLYMER L'OREAL (FR) 2010-05-27 WO disclosed
EP-2189151-A1 Process for the makeup of skin and/or lips by applying a composition comprising a supramolecular polymer L'OREAL (FR) 2010-05-26 EP disclosed
EP-2189148-A2 Dye composition for keratin fibres comprising a supramolecular polymer based on polyalcene, a pigment and a volatile solvent L'OREAL (FR) 2010-05-26 EP disclosed
US-20070264208-A1 Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process L'OREAL S.A. (FR) 2007-11-15 US disclosed
US-20070189991-A1 Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment L'OREAL S.A. (FR) 2007-08-16 US disclosed
EP-1797868-A1 Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment L'Oréal (FR) 2007-06-20 EP disclosed
EP-1797867-A1 Cosmetic or pharmaceutical composition comprising a copolymer containing at least one ionisable group, and cosmetic treatment L'Oréal (FR) 2007-06-20 EP disclosed
US-3940365-A PHENOLIC ANTIOXIDANT AND AN UREA OR AN OXALIC ACID DIAMIDE OR AN AZODICARBOXYLIC AMIDE HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190274946-A1 AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS KRT18, DSG1, CUTA CYP1A2 3238/4885APP 757/4885ACHE 816/4885
US-20070189991-A1 Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment KRT18, TST, CTH CYP1A2 1799/4885APP 2230/4885ACHE 567/4885
US-10973751-B2 Hair dyeing process comprising a pigment and an aqueous dispersion of supramolecular polymer TYR, NACA, POLR1C CYP1A2 1229/4885APP 643/4885ACHE 2471/4885
US-20070264208-A1 Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process KRT18, DSG1, DSC1 CYP1A2 3770/4885APP 2181/4885ACHE 1231/4885
US-20100154134-A1 COMPOSITION FOR DYEING KERATIN FIBERS, COMPRISING AT LEAST ONE POLYALKENE-BASED SUPRAMOLECULAR POLYMER, AT LEAST ONE PIGMENT AND AT LEAST ONE VOLATILE SOLVENT KRT18, JUP, DSG1 CYP1A2 4238/4885APP 621/4885ACHE 1467/4885
US-20200108007-A1 HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER TYR, NACA, POLR1C CYP1A2 1229/4885APP 643/4885ACHE 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.