Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524508 | 0.78 | MAPT (0.36) | ALDH1A1NOX4CAMKK2MAPTRGS12 | |
| SCHEMBL11523096 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4ENOX4CAMKK2MAPT | |
| SCHEMBL524509 | 0.73 | MCL1 (0.39) | ALDH1A1NOX4CAMKK2MAPTRGS12 | |
| SCHEMBL8856987 | 0.73 | GABRP (0.42) | ALDH1A1KDM4ENOX4CAMKK2MAPT | |
| SCHEMBL5025350 | 0.73 | PLK1 (0.49) | MAPTBCL2L1MCL1KDM4CMAPK1 | |
| SCHEMBL9309430 | 0.73 | KDM4C (0.43) | ALDH1A1KDM4ENOX4CAMKK2MAPT | |
| Hydrochloric Acid SCHEMBL9132950 | 0.72 | HPGD (0.48) | ALDH1A1KDM4ERAB9AKAT2BMAPT | |
| SCHEMBL1839262 | 0.71 | MAPT (0.54) | ALDH1A1KDM4ERAB9ANOX4CAMKK2 | |
| SCHEMBL31479884 | 0.71 | KAT2B (0.48) | ALDH1A1KAT2BMAPTTDP1MEN1 | |
| Hydrochloric Acid SCHEMBL8785708 | 0.70 | MAPT (0.53) | ALDH1A1KDM4ERAB9ANOX4CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978201-A | BASE FOR OPHTHALMOLOGICAL MEDICINAL PREPARATION ON OPTHALMOLOGICAL MEDICINAL FILM | KHROMOV GENNADY LVOVICH | 1976-08-31 | — | — | US | disclosed |
| US-3935303-A | Base for ophthalmological medicinal preparations and on ophthalmological medicinal film | KHROMOV GENNADY LVOVICH | 1976-01-27 | — | — | US | disclosed |