Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514613 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDTDP1L3MBTL1 | |
| SCHEMBL28658068 | 0.80 | HPGD (0.50) | ALDH1A1KDM4EKMT2AGAANPC1 | |
| SCHEMBL28230832 | 0.79 | RAB9A (0.53) | ALDH1A1KDM4EKMT2AGAANPC1 | |
| SCHEMBL28647416 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EKMT2AGAANPC1 | |
| Hydrochloric Acid SCHEMBL9636396 | 0.75 | HPGD (0.45) | ALDH1A1KDM4EKMT2AGAANPC1 | |
| SCHEMBL1484138 | 0.74 | KDM4E (0.51) | ALDH1A1KDM4EKMT2AGAANPC1 | |
| SCHEMBL11388942 | 0.74 | SRC (0.54) | KMT2AGAALMNAPOLBMEN1 | |
| Ethylamine SCHEMBL4450987 | 0.73 | ALDH1A1 (0.51) | ALDH1A1HPGDTDP1 | |
| SCHEMBL11809751 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AGAANPC1 | |
| SCHEMBL7105687 | 0.72 | MAP4K4 (0.42) | ALDH1A1KDM4EKMT2AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936457-A | VASODILATION | WARNER-LAMBERT COMPANY (US) | 1976-02-03 | — | — | US | disclosed |