Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803328 | 0.79 | HTT (0.59) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29975518 | 0.76 | ALDH1A1 (0.56) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1780458 | 0.76 | ALDH1A1 (0.56) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL27212829 | 0.73 | KDM1A (0.58) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1994622 | 0.72 | ADORA2A (0.59) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11801685 | 0.69 | TLR7 (0.49) | MAPTSMN1; SMN2ALDH1A1L3MBTL1ADORA2A | |
| SCHEMBL5269788 | 0.69 | BCAT2 (0.60) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10483749 | 0.69 | ALDH1A1 (1.00) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL15452757 | 0.68 | KDM1A (0.53) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6213388 | 0.68 | MAPT (0.61) | MAPTLMNASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962444-A | Use of 4-thiocyano-quinazolines as fungicides | U.S. PHILIPS CORPORATION (US) | 1976-06-08 | — | — | US | claimed |
| US-3962444-A | Use of 4-thiocyano-quinazolines as fungicides | U.S. PHILIPS CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |