Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741187 | 0.87 | FABP4 (0.68) | FABP4MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL11817704 | 0.82 | TSHR (0.46) | TSHRMAPTTHRBALDH1A1MAPK1 | |
| SCHEMBL8388243 | 0.79 | TSHR (0.54) | TSHRFABP4MAPTALOX5ALDH1A1 | |
| SCHEMBL8180699 | 0.74 | TSHR (0.60) | TSHRFABP4MAPTALDH1A1MAPK1 | |
| SCHEMBL2601348 | 0.71 | TSHR (0.63) | TSHRMAPTALDH1A1MAPK1CDC25B | |
| SCHEMBL8802010 | 0.71 | TSHR (0.50) | TSHRMAPTALOX5ALDH1A1MAPK1 | |
| SCHEMBL17625298 | 0.69 | F10 (0.58) | TSHRMAPTALDH1A1MAPK1LMNA | |
| SCHEMBL7426624 | 0.69 | TSHR (0.50) | TSHRALDH1A1LMNAKDM4EGAA | |
| SCHEMBL23174424 | 0.69 | TSHR (0.62) | TSHRMAPTALDH1A1MAPK1LMNA | |
| SCHEMBL5749832 | 0.69 | TSHR (0.59) | TSHRALDH1A1CDC25BKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956295-A | ANTIINFLAMMATORY | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | claimed |