Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | CTSA | P10619 | 2/20 | 0.41 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814009 | 0.81 | PTGS1 (0.49) | PTGS1ACACBCTSAGRNSORT1 | |
| SCHEMBL11807961 | 0.81 | ACACB (0.41) | PTGS1ACACBCTSAGRNSORT1 | |
| SCHEMBL11812363 | 0.80 | MAPT (0.43) | ACACBCTSA | |
| SCHEMBL11808581 | 0.77 | FFAR1 (0.50) | CAMK2APLA2G10FFAR1 | |
| SCHEMBL11410948 | 0.72 | PTGS1 (0.55) | PTGS1ACACBCTSAGRNSORT1 | |
| SCHEMBL11811234 | 0.71 | PTGS1 (0.61) | PTGS1ACACBFFAR1 | |
| SCHEMBL11819568 | 0.71 | PTGS1 (0.47) | PTGS1ACACBCTSAGRNSORT1 | |
| SCHEMBL11669660 | 0.71 | AKR1B1 (0.52) | PTGS1 | |
| SCHEMBL11812772 | 0.70 | MAPT (0.45) | CTSAHRH3 | |
| SCHEMBL11817548 | 0.69 | ACACB (0.42) | PTGS1ACACBCTSAPLA2G10HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994908-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIRHEUMATIC | SHIONOGI & CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |
| US-3940403-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1976-02-24 | — | — | US | disclosed |