Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834922 | 0.90 | MAPK8 (0.40) | ACACBACACANPC1ALDH1A1RAB9A | |
| SCHEMBL11812772 | 0.88 | MAPT (0.45) | NPC1ALDH1A1RAB9ACTSAMEN1 | |
| SCHEMBL11816241 | 0.84 | ACACB (0.37) | ACACBACACANPC1ALDH1A1RAB9A | |
| SCHEMBL11818826 | 0.82 | ACACB (0.40) | ACACBACACANPC1ALDH1A1RAB9A | |
| SCHEMBL11807961 | 0.81 | ACACB (0.41) | ACACBACACANPC1ALDH1A1RAB9A | |
| SCHEMBL11810268 | 0.78 | CYP1A2 (0.44) | ACACBACACANPC1ALDH1A1RAB9A | |
| SCHEMBL11814009 | 0.76 | PTGS1 (0.49) | ACACBACACANPC1ALDH1A1RAB9A | |
| SCHEMBL29043663 | 0.74 | IDO1 (0.49) | NPC1ALDH1A1RAB9APKMMEN1 | |
| SCHEMBL11817553 | 0.72 | CCNC (0.43) | ACACBNPC1ALDH1A1RAB9APKM | |
| SCHEMBL29043665 | 0.72 | ALDH1A1 (0.58) | NPC1ALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994908-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIRHEUMATIC | SHIONOGI & CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |
| US-3940403-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1976-02-24 | — | — | US | disclosed |