Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814009 | 0.75 | PTGS1 (0.49) | PTGS1KDM4EHRH3NPC1RAB9A | |
| SCHEMBL6120808 | 0.73 | NNMT (0.64) | EGLN1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL11169364 | 0.73 | MAPT (0.49) | EGLN1KDM4ENPC1ALDH1A1GAA | |
| SCHEMBL5575614 | 0.72 | PTGS2 (0.43) | PTGS1CYP1A2CYP2C9LMNA | |
| SCHEMBL18960378 | 0.72 | MEN1 (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11410948 | 0.72 | PTGS1 (0.55) | PTGS1HRH3ACACBCTSAGRN | |
| SCHEMBL19808897 | 0.72 | TDP1 (0.51) | EGLN1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL11808573 | 0.71 | PTGS1 (0.45) | PTGS1HRH3ACACBCTSAGRN | |
| SCHEMBL1345669 | 0.71 | PTGS1 (0.54) | PTGS1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL3817959 | 0.71 | PTGS1 (0.54) | PTGS1KDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940403-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1976-02-24 | — | — | US | claimed |