Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 3/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | CTSA | P10619 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808573 | 0.81 | PTGS1 (0.45) | PTGS1ACACBACACACTSAHRH3 | |
| SCHEMBL11823631 | 0.79 | AKR1C3 (0.45) | PTGS1ACACBACACAFFAR1PTGS2 | |
| SCHEMBL11812772 | 0.77 | MAPT (0.45) | CTSAHRH3ALDH1A1KDM4EHPGD | |
| SCHEMBL11410948 | 0.77 | PTGS1 (0.55) | PTGS1ACACBACACACTSAHRH3 | |
| SCHEMBL18181863 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10GPR84 | |
| SCHEMBL11817548 | 0.76 | ACACB (0.42) | PTGS1ACACBACACACTSAHRH3 | |
| SCHEMBL11819568 | 0.75 | PTGS1 (0.47) | PTGS1ACACBCTSAHRH3ALDH1A1 | |
| SCHEMBL11811234 | 0.75 | PTGS1 (0.61) | PTGS1ACACBALDH1A1KDM4EHPGD | |
| SCHEMBL11810268 | 0.75 | CYP1A2 (0.44) | ACACBACACACTSAHRH3ALDH1A1 | |
| SCHEMBL11834922 | 0.74 | MAPK8 (0.40) | PTGS1ACACBACACACTSAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940403-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1976-02-24 | — | — | US | claimed |