Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.63 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12485500 | 0.82 | CA12 (0.60) | ERN1KMT2AMAPTHTTMEN1 | |
| SCHEMBL13786955 | 0.82 | CA12 (0.60) | ERN1KMT2AMAPTHTTMEN1 | |
| SCHEMBL22624794 | 0.78 | MAPT (0.66) | APAF1ATMSAE1UBA2L3MBTL1 | |
| SCHEMBL28483618 | 0.78 | MAPT (0.66) | APAF1ATMSAE1UBA2L3MBTL1 | |
| SCHEMBL29889077 | 0.77 | APAF1 (0.65) | APAF1ATMSAE1UBA2L3MBTL1 | |
| SCHEMBL22624730 | 0.77 | APAF1 (0.65) | APAF1ATMSAE1UBA2L3MBTL1 | |
| SCHEMBL4627702 | 0.77 | TDP1 (0.49) | APAF1ATMSAE1UBA2L3MBTL1 | |
| SCHEMBL2032350 | 0.77 | TDP1 (0.49) | APAF1ATMSAE1UBA2L3MBTL1 | |
| SCHEMBL2312703 | 0.75 | L3MBTL1 (0.68) | APAF1ATMSAE1UBA2L3MBTL1 | |
| SCHEMBL12417103 | 0.74 | MAPT (0.55) | APAF1ATMSAE1UBA2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933737-A | SULFUR-CONTAINING ORGANOTIN COMPOUNDS AND NON-SULFUR-CONTAINING ORGANOTIN COMPOUNDS | KABEL-UND METALLWERKE GUTEHOFFNUNGSHUTTE AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |