Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | POLB | P06746 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.66 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.59 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22624794 | 1.00 | MAPT (0.66) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL12767390 | 0.78 | MAPT (0.53) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL11809170 | 0.78 | APAF1 (0.63) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9850040 | 0.76 | ALDH1A1 (0.66) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL22624828 | 0.76 | CDK2 (0.56) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL22624746 | 0.75 | MAPT (0.78) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL22624730 | 0.74 | APAF1 (0.65) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL29889077 | 0.74 | APAF1 (0.65) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL28759220 | 0.74 | MAPT (0.76) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL5184493 | 0.73 | FTO (0.56) | MAPTALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229158-A | Compound with antibacterial activity | 香港理工大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-117143060-A | Compound with antibacterial activity | 香港理工大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-111971271-B | Compound with antibacterial activity | 香港理工大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-111971271-A | Compound with antibacterial activity | 香港理工大学 | 2020-11-20 | — | — | CN | disclosed |