Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692199 | 0.88 | CXCR1 (0.43) | PTGS1PTGS2CXCR1CXCR2LMNA | |
| SCHEMBL11734664 | 0.85 | PTGS1 (0.37) | PTGS1PTGS2CXCR1CXCR2LMNA | |
| SCHEMBL14966836 | 0.83 | ABHD10 (0.39) | LMNA | |
| SCHEMBL9185282 | 0.83 | PTGS1 (0.45) | PTGS1PTGS2CXCR1CXCR2LMNA | |
| SCHEMBL14967441 | 0.81 | TSHR (0.39) | LMNATSHR | |
| SCHEMBL11731498 | 0.81 | PTGS1 (0.40) | PTGS1PTGS2CXCR1CXCR2LMNA | |
| SCHEMBL16108652 | 0.81 | HPGD (0.43) | CYP2C9MMP1MMP2MMP9 | |
| SCHEMBL11630575 | 0.77 | CXCR1 (0.33) | CXCR1CXCR2LMNAESR1MMP1 | |
| SCHEMBL11652559 | 0.75 | NAAA (0.38) | — | |
| SCHEMBL11631923 | 0.75 | FDFT1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965161-A | Process of producing a 2-(4-alkylphenyl)-propionic acid | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1976-06-22 | — | — | US | disclosed |
| US-3959349-A | 2-Hydroxy-3(4-alkylphenyl)-3-butenoic acid ester and process for the production thereof | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1976-05-25 | — | — | US | disclosed |