Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731498 | 0.85 | PTGS1 (0.40) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL9692199 | 0.84 | CXCR1 (0.43) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL11809472 | 0.83 | PTGS1 (0.38) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL11734664 | 0.82 | PTGS1 (0.37) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL18316474 | 0.77 | CRHBP (0.44) | TSHRMMP2MMP9 | |
| SCHEMBL11630575 | 0.73 | CXCR1 (0.33) | LMNACXCR1CXCR2ESR1MMP1 | |
| SCHEMBL9750487 | 0.73 | HSD11B1 (0.44) | — | |
| SCHEMBL8776897 | 0.73 | HSD11B1 (0.44) | — | |
| SCHEMBL10539887 | 0.72 | PTGS1 (0.42) | PTGS1PTGS2ALOX5LMNACYP2C9 | |
| SCHEMBL9692353 | 0.72 | BCL2L1 (0.42) | PTGS2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672166-A1 | ENANTIOSELECTIVE PRODUCTION OF CHIRAL CARBOXYLIC ACIDS | SEPRACOR, INC. (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1994010334-A1 | ENANTIOSELECTIVE PRODUCTION OF CHIRAL CARBOXYLIC ACIDS | SEPRACOR, INC. (US) | 1994-05-11 | — | — | WO | claimed |
| US-5273895-A | Oxidizing the aldehyde or hydroxy precursor by an enzyme or Pseudomonas, Aeromonas, Escherichia and Alicaligenes | SEPRACOR, INC. (US) | 1993-12-28 | — | — | US | claimed |
| CN-106258252-B | A kind of biomass straw crushes briquetting all-in-one machine and its method of work | 江苏建筑职业技术学院 | 2018-06-05 | — | — | CN | disclosed |
| EP-0672166-A1 | ENANTIOSELECTIVE PRODUCTION OF CHIRAL CARBOXYLIC ACIDS | SEPRACOR, INC. (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994010334-A1 | ENANTIOSELECTIVE PRODUCTION OF CHIRAL CARBOXYLIC ACIDS | SEPRACOR, INC. (US) | 1994-05-11 | — | — | WO | disclosed |
| US-5273895-A | Oxidizing the aldehyde or hydroxy precursor by an enzyme or Pseudomonas, Aeromonas, Escherichia and Alicaligenes | SEPRACOR, INC. (US) | 1993-12-28 | — | — | US | disclosed |