Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.58 |
| ▸ | RAB9A | P51151 | 12/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | MYC | P01106 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | MECP2 | P51608 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809878 | 0.98 | NPC1 (0.60) | NPC1RAB9APTPN1KMT2ASMN1; SMN2 | |
| SCHEMBL11807161 | 0.85 | NPC1 (0.50) | NPC1RAB9APTPN1KMT2ASMN1; SMN2 | |
| SCHEMBL10334618 | 0.82 | ACMSD (0.62) | PTPN1KMT2AALDH1A1KDM4EALOX15 | |
| SCHEMBL2462821 | 0.81 | ACMSD (0.66) | NPC1RAB9APTPN1KMT2ASMN1; SMN2 | |
| SCHEMBL8579065 | 0.79 | NPC1 (0.55) | NPC1RAB9APTPN1KMT2ASMN1; SMN2 | |
| SCHEMBL11611972 | 0.78 | RAB9A (0.64) | NPC1RAB9APTPN1KMT2ASMN1; SMN2 | |
| SCHEMBL11977551 | 0.78 | NPC1 (0.65) | NPC1RAB9AKMT2ASMN1; SMN2TSHR | |
| SCHEMBL11808339 | 0.77 | PTPN1 (0.46) | NPC1RAB9APTPN1KMT2ASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL11613889 | 0.77 | RAB9A (0.62) | NPC1RAB9APTPN1KMT2ASMN1; SMN2 | |
| SCHEMBL11634742 | 0.76 | PTGS2 (0.50) | NPC1RAB9AKMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939115-A | OXADIAZOLES | EASTMAN KODAK COMPANY (US) | 1976-02-17 | — | — | US | disclosed |