Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MYOC | Q99972 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778961 | 0.89 | LMNA (0.51) | LMNAALDH1A1SMN1; SMN2MMP13CRHBP | |
| SCHEMBL11780654 | 0.86 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2MMP13SLC2A1 | |
| SCHEMBL11782643 | 0.84 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2MMP13CRHBP | |
| SCHEMBL11779835 | 0.82 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2MMP13SLC2A1 | |
| SCHEMBL11777030 | 0.82 | MMP13 (0.44) | LMNAALDH1A1SMN1; SMN2MMP13SLC2A1 | |
| SCHEMBL11780552 | 0.81 | LMNA (0.45) | LMNAALDH1A1SMN1; SMN2MMP13CRHBP | |
| Clefamide SCHEMBL672628 | 0.81 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2MMP13CRHBP | |
| SCHEMBL11780196 | 0.81 | MC4R (0.53) | LMNAALDH1A1SMN1; SMN2MMP13CRHBP | |
| SCHEMBL11780000 | 0.81 | MC4R (0.53) | LMNAALDH1A1SMN1; SMN2MMP13CRHBP | |
| SCHEMBL11780973 | 0.81 | ALDH1A1 (0.50) | LMNAALDH1A1SMN1; SMN2MMP13CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940441-A | BACTERICIDE | STERLING DRUG INC. (US) | 1976-02-24 | — | — | US | disclosed |