Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11827869 | 0.99 | ADRB2 (0.46) | ADRB2KCNH2ADRB1ADRB3TAS1R3 | |
| SCHEMBL11812685 | 0.88 | ADRB3 (0.45) | ADRB2KCNH2ADRB1ADRB3LMNA | |
| Hydrochloric Acid SCHEMBL11806979 | 0.86 | ADRB3 (0.44) | ADRB2KCNH2ADRB1ADRB3LMNA | |
| SCHEMBL11816834 | 0.85 | ADRB2 (0.42) | ADRB2KCNH2ADRB1ADRB3LMNA | |
| SCHEMBL11811907 | 0.82 | ADRB2 (0.42) | ADRB2KCNH2ADRB1ADRB3LMNA | |
| SCHEMBL11818300 | 0.81 | ADRB2 (0.48) | ADRB2KCNH2ADRB1ADRB3LMNA | |
| SCHEMBL11815505 | 0.80 | ALDH1A1 (0.46) | ADRB2KCNH2ADRB1ADRB3LMNA | |
| SCHEMBL11816845 | 0.78 | ADRB2 (0.48) | ADRB2KCNH2ADRB1ADRB3HTR1A | |
| SCHEMBL9768158 | 0.77 | ADRB2 (0.63) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| SCHEMBL9768151 | 0.77 | ADRB2 (0.63) | ADRB2ADRB1ADRB3LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954871-A | ANTIARRHYTHMIA, VASODILATOR, HYPOTENSIVE | CONTINENTAL PHARMA (BE) | 1976-05-04 | — | — | US | claimed |
| US-3954871-A | ANTIARRHYTHMIA, VASODILATOR, HYPOTENSIVE | CONTINENTAL PHARMA (BE) | 1976-05-04 | — | — | US | disclosed |