Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.83 |
| ▸ | MMP1 | P03956 | 16/20 | 0.83 |
| ▸ | PGR | P06401 | 3/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986508 | 1.00 | NR3C1 (0.83) | NR3C1MMP1PGRCYP3A4MEN1 | |
| SCHEMBL7547 | 1.00 | NR3C1 (0.83) | NR3C1MMP1PGRCYP3A4MEN1 | |
| SCHEMBL147590 | 0.99 | NR3C1 (0.82) | NR3C1MMP1PGRCYP3A4MEN1 | |
| SCHEMBL1265487 | 0.99 | NR3C1 (0.82) | NR3C1MMP1PGRCYP3A4MEN1 | |
| Dexamethasone SCHEMBL3681477 | 0.95 | NR3C1 (0.84) | NR3C1MMP1PGRCYP3A4MEN1 | |
| SCHEMBL16094588 | 0.93 | NR3C1 (0.81) | NR3C1MMP1PGRCYP3A4MEN1 | |
| SCHEMBL11582615 | 0.93 | NR3C1 (0.74) | NR3C1MMP1PGRCYP3A4MEN1 | |
| SCHEMBL11583661 | 0.93 | NR3C1 (0.75) | NR3C1MMP1PGRCYP3A4MEN1 | |
| SCHEMBL11582612 | 0.93 | NR3C1 (0.74) | NR3C1MMP1PGRCYP3A4MEN1 | |
| SCHEMBL11582295 | 0.93 | NR3C1 (0.74) | NR3C1MMP1PGRCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3944577-A | Novel pregnane-21-oic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-03-16 | — | — | US | disclosed |