SCHEMBL1265487

SCHEMBL1265487

CC(=O)O[C@]1(C(=O)CO)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C.[NaH]

nearest known ligand 0.82

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 17/20 0.82
MMP1 P03956 16/20 0.82
PGR P06401 3/20 0.81
CYP3A4 P08684 2/20 0.81
MEN1 O00255 1/20 0.81
USP2 O75604 1/20 0.81
KMT2A Q03164 1/20 0.81
HIF1A Q16665 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147590 1.00 NR3C1 (0.82) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL6986508 0.99 NR3C1 (0.83) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11812693 0.99 NR3C1 (0.83) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL7547 0.99 NR3C1 (0.83) NR3C1MMP1PGRCYP3A4MEN1
Dexamethasone SCHEMBL3681477 0.94 NR3C1 (0.84) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL16094588 0.92 NR3C1 (0.81) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11582615 0.92 NR3C1 (0.74) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11583661 0.92 NR3C1 (0.75) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11582612 0.92 NR3C1 (0.74) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11582295 0.92 NR3C1 (0.74) NR3C1MMP1PGRCYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7187980-B2 Cardiac lead with steroid eluting ring OSCOR INC. (US) 2007-03-06 US claimed
US-20070020325-A1 Hydrogel composition HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2007-01-25 US claimed
US-20050271725-A1 Adhesive gel composition for iontophoresis preparation and process for producing the same HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2005-12-08 US claimed
EP-1547579-A1 ADHESIVE GEL COMPOSITION FOR IONTOPHORESIS PREPARATION AND PROCESS FOR PRODUCING THE SAME HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2005-06-29 EP claimed
EP-1441806-A2 CARDIAC LEAD WITH STEROID ELUTING RING Oscor Inc. (US) 2004-08-04 EP claimed
WO-2003041793-A2 CARDIAC LEAD WITH STEROID ELUTING RING OSCOR INC. (US) 2003-05-22 WO claimed
US-20030093136-A1 Cardiac lead with steroid eluting ring WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2003-05-15 US claimed
US-20230285293-A1 PHARMACEUTICAL COMPOSITION OF INTRA-ARTICULAR CORTICOSTEROID FOR PAIN CONTROL TLC BIOPHARMACEUTICALS, INC. 2023-09-14 US disclosed
US-20230285565-A1 POLYTETRAFLUOROETHYLENE CO-POLYMER EMULSIONS W. L. GORE & ASSOCIATES, INC. 2023-09-14 US disclosed
CN-116348093-A Pharmaceutical composition of intra-articular corticosteroid for pain control TLC生物医药公司 2023-06-27 CN disclosed
EP-4192426-A1 PHARMACEUTICAL COMPOSITION OF INTRA-ARTICULAR CORTICOSTEROID FOR PAIN CONTROL TLC Biopharmaceuticals, Inc. (US) 2023-06-14 EP disclosed
US-11642412-B2 Polytetrafluoroethylene co-polymer emulsions W. L. GORE & ASSOCIATES, INC. (US) 2023-05-09 US disclosed
US-20220401626-A1 LIQUID COMPOSITION AND POROUS HARDENED MATERIAL COMPRISING TETRAFLUOROETHYLENE AND VINYL MOIETY CO-POLYMERS W. L. GORE & ASSOCIATES, INC. 2022-12-22 US disclosed
US-20040054389-A1 Implantable cardiac lead having removable fluid delivery port WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2004-03-18 US disclosed
WO-2004011081-A1 EPICARDIAL SCREW-IN LEAD OSCOR INC. (US) 2004-02-05 WO disclosed
US-6671562-B2 High impedance drug eluting cardiac lead OSCOR INC. 2003-12-30 US disclosed
WO-2003041793-A2 CARDIAC LEAD WITH STEROID ELUTING RING OSCOR INC. (US) 2003-05-22 WO disclosed
WO-2003041792-A2 HIGH IMPEDANCE DRUG ELUTING CARDIAC LEAD OSCOR INC. (US) 2003-05-22 WO disclosed
US-20030093136-A1 Cardiac lead with steroid eluting ring WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2003-05-15 US disclosed
US-20030093138-A1 High impedance drug eluting cardiac lead WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2003-05-15 US disclosed