SCHEMBL7547

SCHEMBL7547

CC(=O)O[C@]1(C(=O)CO)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C

nearest known ligand 0.83

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 17/20 0.83
MMP1 P03956 16/20 0.83
PGR P06401 3/20 0.82
CYP3A4 P08684 2/20 0.82
MEN1 O00255 1/20 0.82
USP2 O75604 1/20 0.82
KMT2A Q03164 1/20 0.82
HIF1A Q16665 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6986508 1.00 NR3C1 (0.83) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11812693 1.00 NR3C1 (0.83) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL147590 0.99 NR3C1 (0.82) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL1265487 0.99 NR3C1 (0.82) NR3C1MMP1PGRCYP3A4MEN1
Dexamethasone SCHEMBL3681477 0.95 NR3C1 (0.84) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL16094588 0.93 NR3C1 (0.81) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11582615 0.93 NR3C1 (0.74) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11583661 0.93 NR3C1 (0.75) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11582612 0.93 NR3C1 (0.74) NR3C1MMP1PGRCYP3A4MEN1
SCHEMBL11582295 0.93 NR3C1 (0.74) NR3C1MMP1PGRCYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12478 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES TRAILHEAD BIOSYSTEMS INC (US) 2026-05-07 US claimed
US-20260108657-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING OSTEOARTHRITIS INSIGNIA PHARMACEUTICALS, LLC (US) 2026-04-23 US claimed
EP-4725558-A2 IMMUNOABLATIVE THERAPIES AVM Biotechnology, LLC (US) 2026-04-15 EP claimed
EP-4719194-A1 METHODS FOR INCORPORATING THERAPEUTIC AGENTS INTO ANALYTE SENSORS Abbott Diabetes Care, Inc. (US) 2026-04-08 EP claimed
EP-4710918-A1 OPHTHALMIC PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR, OPHTHALMIC KIT CONTAINING OPHTHALMIC PHARMACEUTICAL COMPOSITION, AND USE Shenyang Xingqi Pharmaceutical Co., Ltd. (CN) 2026-03-18 EP claimed
EP-3860612-B1 IMMUNOABLATIVE THERAPIES AVM BIOTECHNOLOGY LLC (US) 2026-03-04 EP claimed
US-12551148-B2 Systems and methods for compensating for agent elution MEDTRONIC MINIMED, INC. (US) 2026-02-17 US claimed
EP-4683679-A1 METHOD FOR DIAGNOSING AND TREATING NIS-EXPRESSING CARCINOMAS AND METASTASES NUSKE, Andreas (DE) 2026-01-28 EP claimed
US-12491289-B2 Pharmaceutical compositions for treating osteoarthritis INSIGNIA PHARMACEUTICALS, LLC (US) 2025-12-09 US claimed
EP-4654956-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING OSTEOARTHRITIS Insignia Pharmaceuticals, LLC (US) 2025-12-03 EP claimed
EP-0512050-A4 DERIVATIVES OF CYCLODEXTRINS EXHIBITING ENHANCED AQUEOUS SOLUBILITY AND THE USE THEREOF 1993-04-21 EP claimed
CN-1066395-A A kind of preparation method of cortical hormone compound preparation for external use ZHANJIANG MEDICAL COLLEGE (CN) 1992-11-25 CN claimed
EP-0512050-A1 DERIVATIVES OF CYCLODEXTRINS EXHIBITING ENHANCED AQUEOUS SOLUBILITY AND THE USE THEREOF THE UNIVERSITY OF KANSAS (US) 1992-11-11 EP claimed
CN-1065996-A Reduce the method for side reaction of trichosanthes kirilowii protein SHANGHAI INST ORGANIC CHEM (CN) 1992-11-11 CN claimed
US-5134127-A Sulfoalkyl Ethers, Solubilizing Agents for Drugs UNIVERSITY OF KANSAS (US) 1992-07-28 US claimed
WO-1991011172-A1 DERIVATIVES OF CYCLODEXTRINS EXHIBITING ENHANCED AQUEOUS SOLUBILITY AND THE USE THEREOF THE UNIVERSITY OF KANSAS (US) 1991-08-08 WO claimed
US-4879274-A IMPROVED ABSORPTION KAO CORPORATION (JP) 1989-11-07 US claimed
US-4775667-A ETHYLENE GLYCOL MONOSALICYLATE, A CORTICOSTEROID AND L-MENTHOL MIXTURE SHIONOGI & CO., LTD. (JP) 1988-10-04 US claimed
US-4294852-A WATER, AN ALIPHATIC ALCOHOL AND AN ORGANIC ACID TO ADJUST THE PH OF THE VEHICLE JOHNSON & JOHNSON (US) 1981-10-13 US claimed
US-3962430-A Sterilization of solid non-electrolyte medicinal agents employing sodium chloride MERCK & CO., INC. (US) 1976-06-08 US claimed