Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.65 |
| ▸ | PGR | P06401 | 5/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | USP2 | O75604 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MLNR | O43193 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813494 | 1.00 | NR3C1 (0.65) | NR3C1PGRCYP3A4USP2LMNA | |
| SCHEMBL11853850 | 0.93 | NR3C1 (0.65) | NR3C1PGRCYP3A4USP2LMNA | |
| SCHEMBL11853853 | 0.93 | NR3C1 (0.65) | NR3C1PGRCYP3A4USP2LMNA | |
| Betamethasone Benzoate SCHEMBL11878006 | 0.91 | NR3C1 (0.77) | NR3C1PGRCYP3A4USP2MEN1 | |
| Betamethasone Benzoate SCHEMBL11877997 | 0.91 | NR3C1 (0.77) | NR3C1PGRCYP3A4USP2MEN1 | |
| Betamethasone Benzoate SCHEMBL49469 | 0.91 | NR3C1 (0.77) | NR3C1PGRCYP3A4USP2MEN1 | |
| Betamethasone Benzoate SCHEMBL2954925 | 0.91 | NR3C1 (0.77) | NR3C1PGRCYP3A4USP2MEN1 | |
| SCHEMBL11689579 | 0.90 | NR3C1 (0.69) | NR3C1PGRCYP3A4USP2LMNA | |
| SCHEMBL11690649 | 0.90 | NR3C1 (0.69) | NR3C1PGRCYP3A4USP2LMNA | |
| SCHEMBL11813525 | 0.90 | NR3C1 (0.69) | NR3C1PGRCYP3A4USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3944577-A | Novel pregnane-21-oic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-03-16 | — | — | US | claimed |
| US-3944577-A | Novel pregnane-21-oic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-03-16 | — | — | US | disclosed |