Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRG | P23470 | 3/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820339 | 0.89 | IGF2BP2 (0.46) | PTPRGPPARDPPARAEPHX1MEN1 | |
| SCHEMBL11829021 | 0.88 | PPARD (0.43) | PTPRGPPARDPPARAAKR1C2AKR1C1 | |
| SCHEMBL11818371 | 0.88 | PTPRG (0.44) | PTPRGPPARDPPARAAKR1C2AKR1C1 | |
| SCHEMBL11818503 | 0.88 | PPARA (0.45) | PPARDPPARAEPHX1MRGPRX4KCNK2 | |
| SCHEMBL11822454 | 0.80 | KDM5A (0.43) | PTPRGPPARDPPARAHTTEPHX1 | |
| SCHEMBL11819449 | 0.79 | CYP1A2 (0.48) | HTTEPHX1MEN1POLBHPGD | |
| SCHEMBL11817938 | 0.78 | TRPV1 (0.46) | AKR1C2AKR1C1EPHX1HPGDMRGPRX4 | |
| SCHEMBL11817917 | 0.77 | PTPRG (0.47) | PTPRGRHEBHTTMEN1LMNA | |
| SCHEMBL11816465 | 0.77 | KDM5A (0.41) | PTPRGEPHX1MRGPRX4ARKCNK2 | |
| SCHEMBL11821210 | 0.77 | MEN1 (0.47) | AKR1C2HTTMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |