Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.45 |
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.42 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820339 | 0.89 | IGF2BP2 (0.46) | PPARAPPARDKCNK2KCNK10IGF2BP2 | |
| SCHEMBL11829021 | 0.88 | PPARD (0.43) | PPARAPPARDKCNK2KCNK10IGF2BP2 | |
| SCHEMBL11818371 | 0.88 | PTPRG (0.44) | PPARAPPARDKCNK2KCNK10IGF2BP2 | |
| SCHEMBL11814817 | 0.88 | PTPRG (0.48) | PPARAPPARDKCNK2KCNK10EPHX1 | |
| SCHEMBL10744475 | 0.83 | PPARD (0.49) | PPARAPPARDPPARGFKBP1ATRPV1 | |
| SCHEMBL11822454 | 0.80 | KDM5A (0.43) | PPARAPPARDPPARGIGF2BP2EPHX1 | |
| SCHEMBL10746094 | 0.79 | FKBP1A (0.53) | PPARAPPARDPPARGFKBP1A | |
| SCHEMBL11819449 | 0.79 | CYP1A2 (0.48) | CHRM5EPHX1MRGPRX4 | |
| SCHEMBL11818931 | 0.79 | FKBP1A (0.50) | PPARAPPARDPPARGFKBP1AMRGPRX4 | |
| SCHEMBL11825095 | 0.78 | FKBP1A (0.52) | PPARAPPARDPPARGFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |