Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPRG | P23470 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814817 | 0.89 | PTPRG (0.48) | EPHX1MRGPRX4PTPRCPTPRGLMNA | |
| SCHEMBL11818371 | 0.89 | PTPRG (0.44) | IGF2BP2MAPK14KDM5AKDM4CKDM5B | |
| SCHEMBL11829021 | 0.89 | PPARD (0.43) | IGF2BP2MAPK14KDM5AKDM4CKDM5B | |
| SCHEMBL11818503 | 0.89 | PPARA (0.45) | IGF2BP2EPHX1MRGPRX4PPARDPPARA | |
| SCHEMBL11822454 | 0.88 | KDM5A (0.43) | IGF2BP2MAPK14KDM5AKDM4CKDM5B | |
| SCHEMBL11819449 | 0.87 | CYP1A2 (0.48) | MAPK14KDM5AKDM4CKDM5BEPHX1 | |
| SCHEMBL11817938 | 0.86 | TRPV1 (0.46) | IGF2BP2MAPK14KDM5AKDM4CKDM5B | |
| SCHEMBL11816465 | 0.84 | KDM5A (0.41) | IGF2BP2MAPK14KDM5AKDM4CKDM5B | |
| SCHEMBL11821210 | 0.84 | MEN1 (0.47) | KDM5AKDM4CKDM5BMRGPRX4LMNA | |
| SCHEMBL10746094 | 0.80 | FKBP1A (0.53) | PTPRCPTPRGKDM4EPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |