Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822454 | 0.88 | KDM5A (0.43) | CYP1A2KDM5AKDM4CKDM5BMAPK14 | |
| SCHEMBL11820339 | 0.87 | IGF2BP2 (0.46) | KDM5AKDM4CKDM5BMAPK14KDM4E | |
| SCHEMBL11821210 | 0.84 | MEN1 (0.47) | CYP1A2KDM5AKDM4CKDM5BRAB9A | |
| SCHEMBL11816465 | 0.82 | KDM5A (0.41) | KDM5AKDM4CKDM5BMAPK14EPHX1 | |
| SCHEMBL11816258 | 0.82 | CYP1A2 (0.46) | CYP1A2APEX1RAB9AKDM4EHPGD | |
| SCHEMBL11826777 | 0.81 | CYP1A2 (0.46) | CYP1A2APEX1RAB9AKDM4EPOLB | |
| SCHEMBL11818371 | 0.79 | PTPRG (0.44) | KDM5AKDM4CKDM5BMAPK14KDM4E | |
| SCHEMBL11814817 | 0.79 | PTPRG (0.48) | RAB9APOLBEPHX1HPGDMEN1 | |
| SCHEMBL11829021 | 0.79 | PPARD (0.43) | KDM5AKDM4CKDM5BMAPK14KDM4E | |
| SCHEMBL11818503 | 0.79 | PPARA (0.45) | CHRM5EPHX1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |