Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930005 | 0.74 | EPHB4 (0.40) | IKBKBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23309625 | 0.70 | HSD17B10 (0.37) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL31531435 | 0.69 | MAPT (0.47) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL20014923 | 0.67 | MAPK1 (0.58) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL7990423 | 0.66 | — | — | |
| SCHEMBL1820046 | 0.66 | — | — | |
| SCHEMBL3337813 | 0.66 | PTK2 (0.49) | ALDH1A1MEN1KMT2AMAPK1PKM | |
| SCHEMBL10653177 | 0.66 | SMN1; SMN2 (0.56) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7418328 | 0.65 | — | — | |
| SCHEMBL3615750 | 0.63 | MAPT (0.62) | ALDH1A1KDM4EKMT2APKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956315-A | Herbicidal N-(3-cyano-4-alkylthien-2-yl) ureas | CHEVRON RESEARCH COMPANY (US) | 1976-05-11 | — | — | US | disclosed |