Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26474681 | 0.86 | ALDH1A1 (0.53) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL11468077 | 0.86 | TP53 (0.62) | MAPK1ADRA2AADRA2BADRA2CMEN1 | |
| SCHEMBL13019308 | 0.85 | SMN1; SMN2 (0.54) | MAPK1ADRA2AADRA2BADRA2CMEN1 | |
| SCHEMBL2989345 | 0.84 | LMNA (0.51) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL14882857 | 0.83 | ADRA2A (0.52) | MAPK1ADRA2AADRA2BADRA2CMEN1 | |
| SCHEMBL5233999 | 0.82 | POLB (0.54) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL4158380 | 0.82 | NPSR1 (0.52) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL2984306 | 0.82 | ALDH1A1 (0.52) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL2979292 | 0.81 | MEN1 (0.54) | MAPK1ADRA2AADRA2BADRA2CMEN1 | |
| SCHEMBL13041354 | 0.81 | NPSR1 (0.51) | ADRA2AADRA2BADRA2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054846-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |