Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 15/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 2/20 | 0.52 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821563 | 0.78 | ESR1 (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1278616 | 0.77 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL11820836 | 0.76 | TAS2R14 (0.63) | TAS2R14MEN1KMT2AALDH1A1CXCR3 | |
| SCHEMBL1615782 | 0.76 | TAS2R14 (0.83) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL11821964 | 0.76 | TAS2R14 (0.65) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL11814174 | 0.76 | TAS2R14 (0.61) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL1278788 | 0.76 | TAS2R14 (0.97) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL11819862 | 0.75 | SMN1; SMN2 (0.52) | KMT2AALDH1A1PTGES | |
| SCHEMBL11829733 | 0.75 | SMN1; SMN2 (0.52) | KMT2AALDH1A1PTGES | |
| SCHEMBL3563700 | 0.75 | TAS2R14 (0.72) | TAS2R14MEN1KMT2ACXCR3PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |