Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820346 | 0.82 | NR4A2 (0.47) | NR4A2MRGPRX4AREPHX1SRD5A2 | |
| SCHEMBL11823732 | 0.81 | GFER (0.54) | NR4A2EPHX1NPSR1L3MBTL1MAPT | |
| SCHEMBL11820534 | 0.78 | EPHX1 (0.51) | NR4A2EPHX1NPSR1L3MBTL1MAPT | |
| SCHEMBL11825039 | 0.77 | DAO (0.53) | NR4A2MRGPRX4EPHX1SRD5A2MAPT | |
| SCHEMBL7825081 | 0.76 | L3MBTL1 (0.69) | EPHX1NPSR1L3MBTL1MAPTHTT | |
| SCHEMBL11820878 | 0.76 | GSTP1 (0.47) | SRD5A2MAPTHTTLMNAALDH1A1 | |
| SCHEMBL16298245 | 0.74 | MRGPRX4 (0.66) | NR4A2MRGPRX4SRD5A2MAPT | |
| SCHEMBL11821491 | 0.73 | MEN1 (0.45) | EPHX1NPSR1L3MBTL1MAPTHTT | |
| SCHEMBL2721465 | 0.73 | NR4A2 (0.66) | NR4A2MRGPRX4SRD5A2MAPT | |
| SCHEMBL10746094 | 0.72 | FKBP1A (0.53) | L3MBTL1HPGDALDH1A1GFERCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |