Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816938 | 0.91 | GFER (0.44) | MEN1KMT2AGFEREPHX1CA2 | |
| SCHEMBL11818479 | 0.91 | CA2 (0.46) | MEN1KMT2ACA2CA4ALDH1A1 | |
| SCHEMBL11820018 | 0.88 | CA2 (0.53) | MEN1KMT2ACA2CA4L3MBTL1 | |
| SCHEMBL11814899 | 0.87 | PPARD (0.43) | CA2CA4L3MBTL1CA12CA1 | |
| SCHEMBL11818248 | 0.87 | CA2 (0.43) | MEN1KMT2ACA2CA4NPSR1 | |
| SCHEMBL11823732 | 0.86 | GFER (0.54) | GFEREPHX1NPSR1MAPTL3MBTL1 | |
| SCHEMBL11818557 | 0.85 | FKBP1A (0.47) | CA2CA4HPGDALDH1A1KCNQ3 | |
| SCHEMBL11816258 | 0.84 | CYP1A2 (0.46) | MEN1KMT2ACA2CA4HPGD | |
| SCHEMBL11825522 | 0.84 | ALDH1A1 (0.46) | MEN1KMT2ACA2CA4MAPT | |
| SCHEMBL11817917 | 0.81 | PTPRG (0.47) | MEN1KMT2ACA2CA4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |