Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811978 | 0.86 | NOX1 (0.58) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL29242167 | 0.77 | SNCA (0.65) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11817545 | 0.77 | SNCA (0.45) | MEN1KMT2AMAPTGAANOX1 | |
| SCHEMBL293434 | 0.76 | ALOX5 (0.54) | MEN1KMT2AMAPTNPC1RAB9A | |
| Benzene SCHEMBL28125613 | 0.76 | ALOX5 (0.54) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11823962 | 0.75 | NOX1 (0.49) | MEN1KMT2AMAPTNOTUMLMNA | |
| SCHEMBL11822439 | 0.73 | SNCA (0.61) | MAPTSMN1; SMN2LMNAGAAMAPK1 | |
| SCHEMBL11812879 | 0.72 | NOX1 (0.41) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11442019 | 0.71 | SMN1; SMN2 (0.41) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11818936 | 0.70 | ALDH1A1 (0.49) | MEN1KMT2AMAPTNOTUMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962438-A | Anti-arthritic 1H-pyrimido-(5,4,3-kl)phenothiazine-1,3(2H)-diones and 1-thiones | SMITHKLINE CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |