Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815385 | 0.85 | MRGPRX4 (0.46) | HPGDNPSR1KDM4ECYP1A2MEN1 | |
| SCHEMBL11818181 | 0.80 | MRGPRX4 (0.49) | HPGDNPSR1CYP1A2MEN1KMT2A | |
| SCHEMBL11829691 | 0.76 | MRGPRX4 (0.48) | HPGDNPSR1KDM4EMIFMRGPRX4 | |
| SCHEMBL11816211 | 0.76 | CYP1A2 (0.46) | HPGDNPSR1KDM4EMIFCYP1A2 | |
| SCHEMBL11826777 | 0.76 | CYP1A2 (0.46) | HPGDNPSR1KDM4EMIFCYP1A2 | |
| SCHEMBL24637640 | 0.76 | HPGD (0.54) | HPGDNPSR1KDM4EMIFCYP1A2 | |
| SCHEMBL15818934 | 0.73 | MRGPRX4 (0.57) | HPGDNPSR1KDM4EMIFCYP1A2 | |
| SCHEMBL11770089 | 0.73 | RAB9A (0.53) | HPGDNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL11820243 | 0.71 | MRGPRX4 (0.48) | HPGDKDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL11817937 | 0.71 | FFAR1 (0.53) | HPGDKDM4ECYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |