Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820243 | 0.88 | MRGPRX4 (0.48) | MRGPRX4MEN1KMT2AHPGDKDM4E | |
| SCHEMBL11818176 | 0.85 | HPGD (0.49) | MRGPRX4MEN1KMT2AHPGDKDM4E | |
| SCHEMBL11818815 | 0.83 | MRGPRX4 (0.42) | MRGPRX4MEN1KMT2AHPGDKDM4E | |
| SCHEMBL11820227 | 0.77 | TRPV1 (0.46) | MRGPRX4MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11818108 | 0.76 | PTPRZ1 (0.40) | MRGPRX4MEN1KMT2AHPGDMEP1B | |
| SCHEMBL11817074 | 0.76 | DAO (0.41) | MRGPRX4HPGDALDH1A1AURKATPX2 | |
| SCHEMBL11821351 | 0.71 | AURKA (0.49) | MRGPRX4MEN1KMT2AMEP1BAURKA | |
| SCHEMBL11825039 | 0.71 | DAO (0.53) | MRGPRX4ALDH1A1NR4A2EPHX1PLA2G1B | |
| SCHEMBL24017339 | 0.70 | KCNK2 (0.48) | MRGPRX4MEN1KMT2AAURKATPX2 | |
| SCHEMBL31550001 | 0.69 | AURKA (0.56) | MRGPRX4MEN1KMT2AALDH1A1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017299-A | Phthalimide derivatives as plant growth regulants | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |