Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820145 | 0.87 | MEN1 (0.46) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11810807 | 0.84 | ALDH1A1 (0.41) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11820578 | 0.83 | ALDH1A1 (0.45) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL11815653 | 0.83 | LMNA (0.56) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL31273836 | 0.78 | TDP1 (0.64) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11825039 | 0.78 | DAO (0.53) | MAPTPOLBALDH1A1SRD5A2 | |
| SCHEMBL6794925 | 0.77 | ALDH1A1 (0.51) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11821792 | 0.77 | MAPT (0.48) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11815710 | 0.76 | MEN1 (0.48) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11820878 | 0.76 | GSTP1 (0.47) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |