Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | PTPRG | P23470 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RHOC | P08134 | 2/20 | 0.41 |
| ▸ | RHOA | P61586 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820578 | 0.88 | ALDH1A1 (0.45) | LMNAMEN1KMT2ARAB9AHPGD | |
| SCHEMBL11818505 | 0.83 | MEN1 (0.43) | LMNAMEN1KMT2ARAB9AHPGD | |
| SCHEMBL11825039 | 0.82 | DAO (0.53) | POLBMAPTPLA2G1BATG4BMRGPRX4 | |
| SCHEMBL11816320 | 0.80 | MEN1 (0.49) | LMNAMEN1KMT2ARAB9AHPGD | |
| SCHEMBL15819764 | 0.76 | SIRT2 (0.58) | LMNAMEN1KMT2ARAB9AHPGD | |
| SCHEMBL4551075 | 0.75 | MEN1 (0.64) | LMNAMEN1KMT2ARAB9AHPGD | |
| SCHEMBL11853927 | 0.75 | TRPV4 (0.45) | LMNAMEN1KMT2ARAB9AHPGD | |
| SCHEMBL11820145 | 0.75 | MEN1 (0.46) | LMNAMEN1KMT2AHPGDPOLB | |
| SCHEMBL11819492 | 0.74 | DAO (0.43) | HPGDPOLBMRGPRX4ALDH1A1DAO | |
| SCHEMBL11770007 | 0.73 | POLB (0.50) | LMNAMEN1KMT2ARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |