Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
| ▸ | VEGFA | P15692 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867426 | 0.85 | EPAS1 (0.32) | ALDH1A1EPAS1CYP3A4GLP1RVEGFA | |
| SCHEMBL11863525 | 0.85 | EPAS1 (0.32) | EPAS1MAPTGLP1RVEGFA | |
| SCHEMBL11818396 | 0.80 | ALDH1A1 (0.40) | ALDH1A1EPAS1CYP3A4GLP1RVEGFA | |
| SCHEMBL11857518 | 0.78 | EPAS1 (0.33) | ALDH1A1EPAS1CYP3A4GLP1RVEGFA | |
| SCHEMBL11860310 | 0.78 | EPAS1 (0.33) | ALDH1A1EPAS1CYP3A4MAPTGLP1R | |
| SCHEMBL11862605 | 0.77 | EPAS1 (0.35) | ALDH1A1EPAS1CYP3A4GLP1RVEGFA | |
| SCHEMBL11863601 | 0.76 | DCTPP1 (0.36) | ALDH1A1EPAS1CYP3A4GLP1RVEGFA | |
| SCHEMBL11819346 | 0.76 | ALDH1A1 (0.34) | ALDH1A1EPAS1CYP3A4MAPTVEGFA | |
| SCHEMBL11867650 | 0.76 | MEN1 (0.38) | ALDH1A1EPAS1MAPTGLP1RVEGFA | |
| SCHEMBL11816808 | 0.76 | ALDH1A1 (0.38) | ALDH1A1EPAS1CYP3A4MAPTVEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954792-A | 2-Dialkylamino-5-trifluoromethyl-7-nitrobenzimidazoles | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
| US-3932434-A | IMMUNOSUPPRESSANTS | ELI LILLY AND COMPANY (US) | 1976-01-13 | — | — | US | disclosed |