Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 6/20 | 0.32 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11857518 | 0.90 | EPAS1 (0.33) | EPAS1LMNAHPGDSMN1; SMN2GLP1R | |
| SCHEMBL11863601 | 0.89 | DCTPP1 (0.36) | EPAS1LMNAHPGDSMN1; SMN2GLP1R | |
| SCHEMBL11859049 | 0.89 | CYP1A2 (0.37) | EPAS1LMNAHPGDSMN1; SMN2GLP1R | |
| SCHEMBL11863525 | 0.88 | EPAS1 (0.32) | EPAS1LMNAGLP1RVEGFA | |
| SCHEMBL11818540 | 0.85 | ALDH1A1 (0.32) | EPAS1GLP1RVEGFACYP3A4ALDH1A1 | |
| SCHEMBL11810808 | 0.82 | LMNA (0.39) | EPAS1LMNAHPGDSMN1; SMN2DCTPP1 | |
| SCHEMBL11860310 | 0.81 | EPAS1 (0.33) | EPAS1LMNAHPGDGLP1RVEGFA | |
| SCHEMBL11869452 | 0.81 | EPAS1 (0.37) | EPAS1LMNAHPGDSMN1; SMN2DCTPP1 | |
| SCHEMBL11811344 | 0.81 | DHFR (0.30) | ABL1 | |
| SCHEMBL11862605 | 0.81 | EPAS1 (0.35) | EPAS1HPGDGLP1RDCTPP1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954788-A | INTERMEDIATES FOR HERBIDIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |