Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTPRG | P23470 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814899 | 0.93 | PPARD (0.43) | FKBP1AKDM1APPARDCA2CA4 | |
| SCHEMBL11821491 | 0.85 | MEN1 (0.45) | KCNQ3KCNQ2CA2CA4ALDH1A1 | |
| SCHEMBL11820018 | 0.84 | CA2 (0.53) | CA2CA4ALDH1A1PTPRGCA12 | |
| SCHEMBL10746094 | 0.83 | FKBP1A (0.53) | FKBP1APPARDKCNQ3KCNQ2CA2 | |
| SCHEMBL11817140 | 0.83 | CA2 (0.42) | FKBP1ACA2CA4ALDH1A1PTPRG | |
| SCHEMBL11817917 | 0.83 | PTPRG (0.47) | KDM1ACA2CA4HPGDPTPRG | |
| SCHEMBL11817749 | 0.83 | PTPRG (0.44) | KDM1ACA2CA4ALDH1A1PTPRG | |
| SCHEMBL11838590 | 0.83 | LMNA (0.40) | CA2CA4KDM4EALDH1A1HPGD | |
| SCHEMBL11818931 | 0.83 | FKBP1A (0.50) | FKBP1APPARDKDM4EALDH1A1HPGD | |
| SCHEMBL11825095 | 0.82 | FKBP1A (0.52) | FKBP1APPARDKCNQ3KCNQ2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |