Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819909 | 0.83 | GAA (0.46) | GAAMEN1KMT2APOLBMMP1 | |
| SCHEMBL11815680 | 0.83 | MEN1 (0.48) | GAAMEN1KMT2APOLBMMP1 | |
| SCHEMBL11816846 | 0.82 | MEN1 (0.49) | GAAMEN1KMT2APOLBMMP1 | |
| SCHEMBL11810807 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2APOLBMMP1MMP2 | |
| SCHEMBL11822223 | 0.74 | MEN1 (0.46) | MEN1KMT2APOLBCYP3A4CYP2C9 | |
| SCHEMBL11819988 | 0.74 | LMNA (0.46) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11827554 | 0.72 | KMT2A (0.43) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6794925 | 0.71 | ALDH1A1 (0.51) | GAAMEN1KMT2APOLBCYP3A4 | |
| SCHEMBL11816911 | 0.71 | CA12 (0.47) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL11822961 | 0.71 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |