Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819309 | 0.90 | ALDH1A1 (0.43) | LMNAALDH1A1MCL1BCL2A1ESR1 | |
| SCHEMBL11822961 | 0.86 | ALDH1A1 (0.49) | LMNAALDH1A1MCL1BCL2A1MEN1 | |
| SCHEMBL11816930 | 0.85 | TAS2R14 (0.59) | MEN1KMT2ATAS2R14PTGES | |
| SCHEMBL11815605 | 0.81 | CA12 (0.46) | ALDH1A1MCL1BCL2A1MEN1KMT2A | |
| SCHEMBL11823334 | 0.79 | MCL1 (0.44) | LMNAALDH1A1MCL1BCL2A1MEN1 | |
| SCHEMBL11814493 | 0.77 | ALDH1A1 (0.49) | LMNAALDH1A1MEN1KMT2ATAS2R14 | |
| SCHEMBL11820801 | 0.75 | NPC1 (0.45) | LMNAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11818097 | 0.75 | KMT2A (0.49) | LMNAALDH1A1ESR1MEN1KMT2A | |
| SCHEMBL11817351 | 0.75 | MEN1 (0.46) | LMNAALDH1A1MCL1BCL2A1ESR1 | |
| SCHEMBL11817412 | 0.75 | CA2 (0.52) | LMNAALDH1A1MCL1BCL2A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |