Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.54 |
| ▸ | CA2 | P00918 | 13/20 | 0.54 |
| ▸ | CA4 | P22748 | 6/20 | 0.54 |
| ▸ | CA9 | Q16790 | 6/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA11 | O75493 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3501152 | 0.85 | CA1 (0.69) | CA1CA2CA4CA9CA12 | |
| SCHEMBL13411701 | 0.79 | ALDH1A1 (0.49) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11561420 | 0.78 | CA2 (0.51) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11560868 | 0.78 | CA1 (0.49) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11815501 | 0.76 | CA1 (0.50) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11562150 | 0.76 | CA1 (0.53) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11563706 | 0.75 | CA1 (0.47) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11666192 | 0.73 | CA1 (0.47) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11559048 | 0.71 | MAPT (0.52) | CA1CA2CA4CA9CA12 | |
| SCHEMBL11188939 | 0.71 | SMN1; SMN2 (0.63) | CA1CA2CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972706-A | SUBSTITUTED THIADIAZOL-2-YL-UREAS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |