Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712811 | 0.82 | MAPT (0.65) | MAPTRAB9APOLBKMT2ATP53 | |
| SCHEMBL11821585 | 0.75 | CA1 (0.54) | CA1CA2CA9CA12CA3 | |
| SCHEMBL11561420 | 0.71 | CA2 (0.51) | CA1CA2CA9CA12CA3 | |
| SCHEMBL11562150 | 0.69 | CA1 (0.53) | CA1CA2CA9MAPTCA12 | |
| SCHEMBL11560868 | 0.68 | CA1 (0.49) | CA1CA2CA9MAPTCA12 | |
| SCHEMBL13411701 | 0.68 | ALDH1A1 (0.49) | CA1CA2CA9RAB9ACA12 | |
| SCHEMBL11666192 | 0.67 | CA1 (0.47) | CA1CA2CA9CA12CA3 | |
| SCHEMBL11559048 | 0.65 | MAPT (0.52) | CA1CA2CA9MAPTCA12 | |
| SCHEMBL22118520 | 0.64 | CA1 (1.00) | CA1CA2CA9CA12CA3 | |
| SCHEMBL11558636 | 0.64 | MAPT (0.50) | CA1CA2CA9MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165229-A | SUBSTITUTED THIADIAZOL-2-YLUREA | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |