Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 12/20 | 0.59 |
| ▸ | NPC1 | O15118 | 11/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608963 | 0.84 | PTGS1 (0.85) | PTGS1PTGS2RAB9ANPC1ALDH1A1 | |
| Miroprofen SCHEMBL26767 | 0.84 | PTGS2 (1.00) | PTGS1PTGS2RAB9ANPC1ALDH1A1 | |
| Iodomethane SCHEMBL11823151 | 0.83 | PTGS1 (0.62) | PTGS1PTGS2RAB9ANPC1ALDH1A1 | |
| Miroprofen SCHEMBL11832509 | 0.83 | PTGS2 (0.97) | PTGS1PTGS2RAB9ANPC1ALDH1A1 | |
| SCHEMBL11822617 | 0.83 | PTGS1 (0.79) | PTGS1PTGS2RAB9ANPC1ALDH1A1 | |
| SCHEMBL11819076 | 0.83 | PTGS1 (0.79) | PTGS1PTGS2RAB9ANPC1ALDH1A1 | |
| SCHEMBL11822472 | 0.82 | PTGS1 (0.61) | PTGS1PTGS2RAB9ANPC1ALDH1A1 | |
| SCHEMBL12970268 | 0.82 | RAB9A (0.63) | PTGS1PTGS2RAB9ANPC1ALDH1A1 | |
| SCHEMBL11826121 | 0.82 | KDM4E (0.59) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL15486399 | 0.81 | PTGS1 (0.68) | PTGS1PTGS2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978071-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1976-08-31 | — | — | US | disclosed |